5-Hydroxytryptophan, commonly shortened to 5-HTP, is a naturally occurring amino acid derivative isolated from the seeds of Griffonia simplicifolia. It is a widely adopted raw material in dietary supplement development and functional food formulation, thanks to its well-documented role in supporting the human body’s natural serotonin generation. As a critical intermediate molecule in the endogenous biosynthesis pathway of serotonin, 5-HTP is a staple ingredient in products designed to support steady mood balance, gentle relaxation, and improved overall sleep quality.
Core Product Details
| Category | Specific Information |
|---|---|
| Official Product Name | 5-Hydroxytryptophan Extract |
| Common Aliases | 5-HTP, 5-hydroxytryptophan |
| Botanical Source | Griffonia simplicifolia seed |
| Visual Appearance | Pale yellow to off-white fine powder |
| Molecular Formula | C₁₁H₁₂N₂O₃ |
| Molecular Weight | 220.225 |
| CAS Registry Number | 56-69-9 |
| Standard Purity Specification | 98% |
| Compliance Standard | Meets EP (European Pharmacopoeia) or USP (United States Pharmacopeia) requirements |
| Held Qualification Certifications | ISO, Halal, Kosher, full SGS third-party inspection report |
| Sample Policy | Free samples available for qualified buyers |
| Applicable Product Grade | Medical grade and food grade |
Functional Advantages of 5-Hydroxytryptophan Extract
5-HTP is widely recognized across the global nutrition industry for its core function of boosting endogenous serotonin production in the human body. Serotonin is a key neurotransmitter that plays a central role in regulating daily mood patterns, normal sleep cycles, and long-term emotional balance. As a result, 5-HTP is a very popular ingredient in dietary supplements developed to encourage deep relaxation, support healthy stress management, and deliver natural sleep support.
It is also frequently integrated into custom functional formulations focused on long-term emotional wellness and balanced, healthy lifestyle support. Due to its natural plant origin and evidence-backed functional properties, 5-HTP extract has been broadly adopted by supplement manufacturers, health product distributors, and nutritional production facilities across all major global markets.
Third-Party Lab Test Report
| Test Item | Required Specification | Actual Test Result | Testing Details |
|---|---|---|---|
| 5-HTP Assay (dry weight basis) | ≥98.00% | 98.29% | HPLC (High Performance Liquid Chromatography) |
| Unspecified Impurity Peak X | Negative | Not Detected | HPLC |
| Appearance | Off-white fine powder | Compliant | Visual inspection |
| Odor | Characteristic mild plant scent | Compliant | Sensory evaluation |
| Loss on Drying | ≤2.00% | 1.52% | 5g sample, 105℃, 3 hours testing condition |
| Total Ash Content | ≤1.00% | 0.67% | 2g sample, 525℃, 3 hours testing condition |
| 80 Mesh Sieve Pass Rate | 95% minimum pass through | Compliant | Standard 80 mesh sieve screening test |
| Total Heavy Metals | ≤10ppm | Compliant | CP2010 standard testing |
| Lead (Pb) Content | ≤2ppm | 0.10ppm | AAS (Atomic Absorption Spectroscopy) |
| Arsenic (As) Content | ≤1ppm | 0.02ppm | AAS |
| Total Plate Count | Max <1000 CFU per gram | Compliant | CP2010 standard testing |
| Combined Yeast & Mold Count | Max <100 CFU per gram | Compliant | CP2010 standard testing |
| E. Coli Presence | Negative | Compliant | CP2010 standard testing |
| Salmonella Presence | Negative | Compliant | CP2010 standard testing |
Storage Guidelines
Store the product in a cool, dry, well-ventilated space. Do not freeze the material, and keep it fully protected from direct sunlight, high heat and excess moisture. When stored under the recommended proper conditions, the extract retains full stable potency for 24 full months.
Why Source 5-Hydroxytryptophan Extract From China Extract Warehouse?
China Extract Warehouse is a professional, experienced 5-HTP extract producer and global supplier, operating a modern GMP-compliant manufacturing facility located in China. We specialize in supplying high-purity standardized botanical extracts, with strict end-to-end quality control protocols implemented from raw material sourcing all the way to final finished product packaging. Our 5-HTP extract is refined with optimized processing techniques to ensure high end-user bioavailability, stable consistent potency, and perfect batch-to-batch uniformity for all our global clients. As a trusted direct factory supplier, we support large-volume bulk ordering, flexible OEM/ODM customization services, and long-term stable cooperative arrangements with supplement brands, regional distributors and nutritional product manufacturers across the world.
Frequently Asked Questions
★ Does 5-Hydroxytryptophan actually work for sleep and mood support?
5-HTP is one of the most widely used ingredients in modern functional nutrition formulas developed to support the body’s natural serotonin production, and serotonin levels are closely linked to healthy mood regulation and normal sleep cycle function. It is a very popular raw material in the global natural wellness product space, particularly for supplements targeted at daily stress management and gentle natural sleep support.
★ Is 5-Hydroxytryptophan safe for regular use?
When consumed within recommended daily dosage limits, 5-HTP is broadly recognized as safe for regular use, and it has been a widely approved dietary supplement ingredient across global markets. As a professional direct factory supplier, we enforce strict full-process quality controls, and can provide official COA (Certificate of Analysis) and MSDS documentation to support your safety verification and local regulatory compliance needs.
★ Is 5-Hydroxytryptophan addictive or habit-forming?
No, 5-HTP is not classified as an addictive or dependency-forming substance. It is a 100% natural plant-derived compound extracted from Griffonia simplicifolia seeds, designed exclusively for use as a nutritional supplement ingredient. It will not create physical or psychological dependency when used at appropriate dosages in compliant product formulations.
★ Can you supply 5-HTP in bulk for product manufacturers and brand operators?
We specialize in large-volume bulk supply for supplement production facilities, nutritional product factories, and global regional distributors. Our scaled manufacturing lines guarantee consistent reliable production capacity and uniform quality to support long-term uninterrupted supply partnerships.
★ Do you provide product samples before formal bulk orders?
We fully support pre-order sample testing for all prospective bulk purchase clients, so you can fully evaluate the extract’s purity, solubility, and compatibility with your specific formulation system before moving to mass production of your own finished products.









