Isotretinoin powder is a pharmaceutical product primarily employed for the treatment of severe acne. In rare cases, it is utilized to prevent specific skin cancers (squamous - cell carcinoma) and to address other forms of cancer. Additionally, it is used to treat harlequin - type ichthyosis, a typically fatal skin disorder, and lamellar ichthyosis. It belongs to the retinoid family, which is related to vitamin A and naturally exists in the human body. Its isomer, retinoic acid, is also an acne - treating drug.

Basic Information

  • Product Name: Isotretinoin powder
  • Other Name: Neovitaminaacid
  • Specification: 99%
  • Appearance: Yellow crystalline powder
  • Molecular Formula: C₂₀H₂₈O₂
  • Molecular Weight: 300.44
  • CAS NO.: 4759 - 48 - 2
  • EINECS NO.: 225 - 296 - 0
  • OEM Service: Available
  • Standard: USP or EP
  • Certifications: ISO, Halal, Kosher, SGS Report
  • Grade: Medical and Cosmetic

Uses of Isotretinoin

Isotretinoin powder is mainly used for severe cystic acne and acne that does not improve with other treatment methods. A significant number of dermatologists also advocate its use for less severe acne cases that have shown resistance to other therapies or may result in physical or psychological scarring. However, it is not advisable for the treatment of prepubertal acne and is not recommended for children under 12 years old.

It is also effective against purulent sweat glands and some severe cases of acne rosacea. It can assist in treating harlequin ichthyosis, flaky ichthyosis, and in cases of pigmented dry skin disease, it can alleviate keratosis. It has been applied in the treatment of the rarely - seen ossifying fibrosis. Moreover, it can be used to treat neuroblastoma, a type of neurocarcinoma.

Effects of Isotretinoin

Isotretinoin powder may impede the growth of long bones in young individuals who are still in the growth phase. Premature epiphyseal closure can occur in acne patients taking the recommended doses of Accutane.

Test Report

TestSpecificationsResult
Assay HPLC98%98.12%
ColorYellowComplies
AppearanceFine PowderComplies
IdentificationIR.UVComplies
OdorCharacteristicComplies
Mesh100% pass 100 meshComplies
Residue on ignitionMAX 0.1%Complies
Loss on drying %MAX 0.5%0.39%
Ash %MAX.1.0%0.52%
Heavy metals PPMMAX.0.002%Complies
Limit of IsotretinoinMAX5.0%3.9%
Organic Volatile ImpuritiesMeet The RequirementsComplies
Microbiology - Total Plate Count<1000cfu/g82cfu/g
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