Glycyl-L-Histidyl-L-Lysine is a naturally - occurring copper complex formed by a glycyl - L - histidyl - L - lysine peptide. Since it consists of three amino acids, it is referred to as a tripeptide. Glycyl - L - Histidyl - L - Lysine has a high affinity for copper. It was initially isolated from human plasma and can also be found in saliva and urine.
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Basic information
| Product Name | Glycyl-L-Histidyl-L-Lysine | Other Name | Copper glycyl-histidyl-lysine,Copper peptide GHK-Cu |
| Specification | More than 99% | Appearance | blue powder |
| Molecular Formula | C14H24N6O4 | Molecular Weight | 340.37816 |
| CAS NO. | 49557-75-7 | EINECS NO. | 1592732-453-0 |
| Standard | USP or EP | Certifications | ISO,Halal,Kosher,SGS |
| Grade | Medical and Cosmetic |
Benefits of Glycyl - L - Histidyl - L - Lysine
- Cosmetic use
It is extensively used in anti - aging cosmetics. Several studies have verified the anti - aging, firming, and anti - wrinkle properties of Glycyl - L - Histidyl - L - lysine.
Abdulghani et al. found that a facial cream containing Glycyl - L - Histidyl - L - Lysine increased collagen in the light - aged skin of 20 female volunteers, outperforming vitamin C and retinoic acid.
Leyden et al. carried out a 12 - week facial study on face creams and eye creams containing Glycyl - L - Histidyl - L - Lysine. Compared with the placebo, it significantly improved skin sagging, clarity, and appearance, reduced fine lines and wrinkle depth, and increased skin density and thickness. The Glycyl - L - Histidyl - L - Lysine eye cream performed better than the vitamin K cream.
Finkley et al. conducted a 12 - week facial study on 67 women. According to biopsy histological analysis, applying Glycyl - L - Histidyl - L - Lysine cream twice a day improved the appearance of aged skin, increased its thickness, reduced wrinkles, and strongly promoted skin keratinocyte proliferation. The same study also showed that the copper peptide Glycyl - L - Histidyl - L - Lysine was non - toxic and non - irritating.
- Hair growth
Glycyl - L - Histidyl - L - Lysine and its analogs were discovered to stimulate hair growth. In some instances, the effectiveness of the synthetic analogs of GHK - Cu was comparable to that of 5% minoxidil.
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Test report
| Analysis Items | Specification | Result |
| Appearance | Blue to purple powder | Complies |
| GHK Purity (By HPLC) | ≥ 97.0% | 99.6% |
| Copper Content | 6.0%〜8.0% | 7.7% |
| Acetic Acid (By HPLC) | ≤ 15.0% | ND |
| PH | 5.0-7.0 | 6.1 |
| Loss on drying | ≤ 8.0% | 5.4% |
| Conclusion: Conform to Specification | ||
